Over-encapsulation

A Meaningful Approach

Capsugel perfected over-encapsulation to meet the needs of customers who desired an easier way to blind solid dosage forms in double-blind studies for clinical trials.

Today, Capsugel is the primary supplier of over-encapsulation capsules with DBcaps® capsules.

Our Solution Provides Advantages

Using DBcaps capsules for your double-blind study can help you get into clinical trials faster in tangible ways, including:

• Precisely over-encapsulate uniquely shaped or wide-diameter tablets so tested actives, comparators and placebos are concealed
• Enable blinding without altering the dosage form which reduces trial bias
• No need for splitting, grinding or coating tablets which can alter the dosage form and add time to the process
• Minimum stability testing and potentially no bioequivalence testing required, reducing your product development time
• Use of inactive excipients or backfill reduces unnecessary regulatory steps
• Capsugel’s experienced scientists have the know-how and technologies to customize the over-encapsulation process to suit an array of clinical trial needs including manual filling
• Available in a convenient DBcaps capsules small box filled with 5,000 capsules for your smaller double blind trials 

Related Links

Formulation support

DBcaps® over-encapsulation capsules